Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7
USERS' SCORE
Good
Based on 9 Reviews
8.6
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Vitamin C (as Ascorbic Acid)
1 g (1,000 mg)
1,111%
Rose Hips Powder (Rosa canina) (Fruit)
25 mg
Citrus Bioflavonoid Complex
25 mg

Top Medical Research Studies

7
Vitamin C aids immune function
We examined how a combination of megadose vitamin C infusions and other treatments might help manage chronic fatigue syndrome, particularly in the context of interstitial pneumonia. Our findings were based on nearly a decade of treating patients, allowing us to gather valuable insights.

We observed that the long-term use of this treatment system significantly reduced the risk of pneumonia recurrence. It also appeared to help prevent the emergence of certain cancers in older patients suffering from interstitial pneumonia. Surprisingly, we found a link between interstitial pneumonia and an increased risk of depression, likely driven by prolonged glucocorticoid use.

While some patients showed promise under this treatment, those battling both interstitial pneumonia and depression responded less favorably. We suggested that increasing the amount of dehydroepiandrosterone in the treatment could be beneficial. Throughout our experience, we noted that the characteristics of chronic fatigue syndrome align closely with those of interstitial pneumonia, arguing against the notion that they should be viewed as separate conditions.

Overall, our approach not only alleviated inflammation but did not suppress the fibrotic processes in the long run. We made modifications to the treatment to lower the risks of vascular complications. The main strength of our treatment lies in creating a hormonal environment that helps tackle immune deficiencies using vitamin C, which faces lower resistance in the body compared to steroid treatments.
Read More
7
Vitamin C effects on CFS
We investigated the potential benefits of vitamin C infusions in treating Chronic Fatigue Syndrome (CFS) through a clinical study. This study looked at patients diagnosed with chronic pneumonia and CFS, focusing on how these patients responded to different vitamin C infusion treatments—both those without the addition of dehydroepiandrosterone (DHEA) and those that included it.

Our analysis revealed that a significant portion of patients experienced symptoms aligning with CFS, characterized by a prolonged illness that required extensive medical care. Patients tended to respond better to a combination of both the old and new vitamin C infusions rather than relying solely on the traditional treatment.

Notably, the combined treatment was more effective, suggesting that there may be underlying issues related to hormone levels in CFS patients that are influenced by vitamin C therapy. However, we also noted potential side effects with the sole use of the new vitamin C infusion. A careful balance between the different infusion approaches is crucial for achieving the best outcomes in CFS management.

Overall, while we observed some promising responses to vitamin C treatments, more research is necessary to fully understand its effectiveness and to optimize treatment strategies for those suffering from chronic fatigue syndrome.
Read More
9
Vitamin C therapy shows potential
We investigated the effects of high dose intravenous vitamin C on patients suffering from chronic fatigue syndrome (CFS) linked to Epstein-Barr virus (EBV) infections. Our analysis included data from 178 patients who had elevated levels of EBV antibodies, alongside 40 who also showed signs of ongoing viral activity. Most of our participants were diagnosed with chronic fatigue syndrome, while others had related conditions such as mononucleosis or general fatigue.

What we found is quite promising. High doses of vitamin C appeared to reduce the duration of disease symptoms and helped decrease antibody levels associated with EBV. Notably, we observed that patients with higher levels of vitamin C in their plasma generally had lower levels of certain EBV antibodies, suggesting a potential link that might help manage symptoms of CFS.

Furthermore, there was an interesting connection between vitamin D levels and EBV antibodies as well. Patients who had high levels of vitamin D showed lower levels of EBV early antigen antibodies. This points towards a holistic approach to managing CFS, where both vitamin C and vitamin D may play beneficial roles. Overall, our findings hint at an encouraging effect of high dose vitamin C therapy in helping those grappling with CFS due to EBV.
Read More

Most Useful Reviews

9.5
Improves overall well-being
As we age, our need for vitamin C increases, especially during times of stress or illness. It contributes positively to the entire organism, helping reduce fatigue, support the nervous system, and improve immune function. At 65, taking 1000 mg with Gaba makes me feel energetic and stress-free.
Read More
9.5
Avoids fatigue effectively
As I’m doing muscle training, I take vitamin C every few hours to prevent fatigue. I trust the Now Foods brand since it has consistently delivered results.
Read More
8.8
Reduced fatigue significantly
I recommend high-dose vitamin therapy. The more I take, the better my fatigue and lethargy have improved. It has also helped reduce cold symptoms. I appreciate the affordable prices, which ease the household burden.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7
  • All Researches
9
Vitamin C therapy shows potential
We investigated the effects of high dose intravenous vitamin C on patients suffering from chronic fatigue syndrome (CFS) linked to Epstein-Barr virus (EBV) infections. Our analysis included data from 178 patients who had elevated levels of EBV antibodies, alongside 40 who also showed signs of ongoing viral activity. Most of our participants were diagnosed with chronic fatigue syndrome, while others had related conditions such as mononucleosis or general fatigue.

What we found is quite promising. High doses of vitamin C appeared to reduce the duration of disease symptoms and helped decrease antibody levels associated with EBV. Notably, we observed that patients with higher levels of vitamin C in their plasma generally had lower levels of certain EBV antibodies, suggesting a potential link that might help manage symptoms of CFS.

Furthermore, there was an interesting connection between vitamin D levels and EBV antibodies as well. Patients who had high levels of vitamin D showed lower levels of EBV early antigen antibodies. This points towards a holistic approach to managing CFS, where both vitamin C and vitamin D may play beneficial roles. Overall, our findings hint at an encouraging effect of high dose vitamin C therapy in helping those grappling with CFS due to EBV.
Read More
8
Vitamin C may aid CFS management
We aimed to understand whether vitamin C infusion treatments could benefit those suffering from chronic fatigue syndrome (CFS). Specifically, we looked at two types of vitamin C infusion sets: one that included dehydroepiandrosterone (the new set) and one without it (the old set). Our investigation involved a male patient diagnosed with CFS, monitoring his health from August 1995 to May 1996.

Initially, the old infusion method, alongside some antibiotics, showed effectiveness in managing the patient’s pneumonia, which was a part of the CFS symptoms. However, over time, pneumonia symptoms returned, prompting us to alternate between the old and new vitamin C treatments along with longer antibiotic use. Remarkably, this switch led to a notable reduction in pneumonia signs.

We found that the new vitamin C infusion treatment dramatically increased urine excretion of certain hormones, suggesting an enhancement of the body’s steroid activities. Notably, some evidence indicated that the dehydroepiandrosterone was converted into testosterone, which could positively influence the CFS control. However, our searches for changes in immune response didn’t yield significant results.

Ultimately, our observations suggest that the new vitamin C treatment could help manage CFS by boosting cortisol and testosterone levels, but additional studies would be necessary to fully understand its effectiveness in isolation.
Read More
7
Vitamin C aids immune function
We examined how a combination of megadose vitamin C infusions and other treatments might help manage chronic fatigue syndrome, particularly in the context of interstitial pneumonia. Our findings were based on nearly a decade of treating patients, allowing us to gather valuable insights.

We observed that the long-term use of this treatment system significantly reduced the risk of pneumonia recurrence. It also appeared to help prevent the emergence of certain cancers in older patients suffering from interstitial pneumonia. Surprisingly, we found a link between interstitial pneumonia and an increased risk of depression, likely driven by prolonged glucocorticoid use.

While some patients showed promise under this treatment, those battling both interstitial pneumonia and depression responded less favorably. We suggested that increasing the amount of dehydroepiandrosterone in the treatment could be beneficial. Throughout our experience, we noted that the characteristics of chronic fatigue syndrome align closely with those of interstitial pneumonia, arguing against the notion that they should be viewed as separate conditions.

Overall, our approach not only alleviated inflammation but did not suppress the fibrotic processes in the long run. We made modifications to the treatment to lower the risks of vascular complications. The main strength of our treatment lies in creating a hormonal environment that helps tackle immune deficiencies using vitamin C, which faces lower resistance in the body compared to steroid treatments.
Read More
7
Vitamin C effects on CFS
We investigated the potential benefits of vitamin C infusions in treating Chronic Fatigue Syndrome (CFS) through a clinical study. This study looked at patients diagnosed with chronic pneumonia and CFS, focusing on how these patients responded to different vitamin C infusion treatments—both those without the addition of dehydroepiandrosterone (DHEA) and those that included it.

Our analysis revealed that a significant portion of patients experienced symptoms aligning with CFS, characterized by a prolonged illness that required extensive medical care. Patients tended to respond better to a combination of both the old and new vitamin C infusions rather than relying solely on the traditional treatment.

Notably, the combined treatment was more effective, suggesting that there may be underlying issues related to hormone levels in CFS patients that are influenced by vitamin C therapy. However, we also noted potential side effects with the sole use of the new vitamin C infusion. A careful balance between the different infusion approaches is crucial for achieving the best outcomes in CFS management.

Overall, while we observed some promising responses to vitamin C treatments, more research is necessary to fully understand its effectiveness and to optimize treatment strategies for those suffering from chronic fatigue syndrome.
Read More
4
Vitamin C in complex disease management
We explored the role of high-dose vitamin C infusions combined with dehydroepiandrosterone-cortisol in treating interstitial pneumonia, often linked with chronic fatigue syndrome. In a clinical setting since 1996, we've seen these treatments used for controlling symptoms and potentially improving outcomes in autoimmune disease management.

However, our findings highlight four key issues. First, it is still debated whether these treatments should continue on a maintenance basis when no acute symptoms are present. Some evidence suggests their ongoing use is crucial for halting an evolving bacterial colony in patients with immune deficiencies.

Second, we noted an emerging problem with drug-resistant bacteria, which posed challenges in treatment effectiveness. New antibiotics, like kanamycin, showed promise in addressing this resistance and improving pneumonia symptoms.

Third, we observed a decline in bone marrow function in one patient over a nine-year observation period, indicating potential fibrosis similar to that seen in lung tissue.

Lastly, we encountered a case where a female patient developed breast cancer during treatment, raising concerns about the risks of prolonged autoimmune conditions in older adults. Interestingly, dehydroepiandrosterone appeared to support hepatic recovery during cancer chemotherapy, suggesting complex interactions between treatments and patient responses.

Overall, while vitamin C plays a role in the treatment approach, the complexities of chronic fatigue syndrome and interstitial pneumonia present challenges that require further investigation.
Read More

User Reviews

USERS' SCORE
Good
Based on 9 Reviews
8.6
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
Improves overall well-being
As we age, our need for vitamin C increases, especially during times of stress or illness. It contributes positively to the entire organism, helping reduce fatigue, support the nervous system, and improve immune function. At 65, taking 1000 mg with Gaba makes me feel energetic and stress-free.
Read More
9.5
Avoids fatigue effectively
As I’m doing muscle training, I take vitamin C every few hours to prevent fatigue. I trust the Now Foods brand since it has consistently delivered results.
Read More
8.8
Reduced fatigue significantly
I recommend high-dose vitamin therapy. The more I take, the better my fatigue and lethargy have improved. It has also helped reduce cold symptoms. I appreciate the affordable prices, which ease the household burden.
Read More
8.8
Essential immunity booster
Vitamin C is undoubtedly an essential immunity booster that reduces fatigue. It contains additional immunity-enhancing flavonoids. A base dose of 1000 mg works well without upsetting my stomach, and it also acts as a great antioxidant.
Read More
8.3
Fatigue much better
I feel significantly better as my fatigue has been greatly reduced.
Read More

Frequently Asked Questions

Chronic Fatigue Syndrome (CFS), also known as Myalgic Encephalomyelitis (ME), is a complex and debilitating condition characterized by profound fatigue that doesn’t improve with rest and worsens with physical or mental activity. This crippling fatigue is often accompanied by a variety of symptoms, including sleep disturbances, cognitive difficulties, muscle pain, and joint pain. Unlike typical tiredness, the fatigue experienced in CFS is long-lasting, and it can significantly hinder everyday activities and overall quality of life.

The precise cause of CFS remains unknown, but it is believed to be influenced by a combination of genetic, environmental, immunological, and psychological factors. Diagnosis primarily relies on a careful assessment of symptoms, as there are no definitive laboratory tests available. Treatment options focus on symptom management and may include lifestyle changes, physical therapy, medication for pain management, and cognitive behavioral therapy. Given the complexity and variability of the condition, individuals with CFS should consult healthcare professionals who specialize in this area to develop personalized management strategies.

Ascorbic acid, commonly known as vitamin C, is a water-soluble vitamin that is essential for various bodily functions, including the synthesis of collagen, the absorption of iron, and the maintenance of a healthy immune system. Found naturally in a variety of fruits and vegetables, especially citrus fruits, strawberries, kiwi, and bell peppers, it serves as a potent antioxidant, helping to protect cells from damage by free radicals. Given that the human body cannot synthesize ascorbic acid on its own, it must be obtained through diet or supplementation.

In addition to its fundamental role in supporting overall health, ascorbic acid has garnered interest for its potential benefits in skincare and wound healing. Topical applications of vitamin C can help reduce the appearance of fine lines and improve skin texture, making it a popular ingredient in various cosmetic formulations. Additionally, it plays a crucial role in the body's ability to repair tissues and produce important neurotransmitters. For those looking to boost their vitamin C intake, incorporating a variety of vitamin C-rich foods into your diet or considering a supplement can be effective strategies.

Based on user reviews, the time it takes to see results from vitamin C supplementation for Chronic Fatigue Syndrome can vary, but many users report noticeable improvements within two weeks to three months. One user mentioned that after just two weeks of taking the supplement, they felt a significant reduction in fatigue and an increase in wellbeing ((Read Review)). Another user indicated that after two months of consistent use, they were able to reduce their dosage while still experiencing increased energy levels and decreased feelings of lethargy ((Read Review)).

Other reviews echoed this sentiment, with another user noting considerable health improvements after approximately three months of use ((Read Review)). This suggests that while you may experience some benefits relatively quickly, sustained use over a couple of months may be necessary for optimal results. Overall, users emphasize the importance of consistency in taking the vitamin to maximize its benefits for managing chronic fatigue symptoms.

The scientific research surrounding the use of vitamin C for Chronic Fatigue Syndrome (CFS) is quite compelling, particularly for patients with an underlying Epstein-Barr virus (EBV) infection. A study involving 178 patients found that high doses of intravenous vitamin C not only reduced the duration of symptoms but also correlated with lower levels of EBV antibodies. This suggests a potential link between vitamin C therapy and symptom management in CFS patients [1]. Additionally, another study indicates that combined treatment with vitamin C infusions and dehydroepiandrosterone showed promising results in alleviating some symptoms associated with CFS [4].

However, while there are positive indicators of vitamin C's effectiveness in managing CFS symptoms, challenges remain. The complexity of CFS and its interplay with other conditions, such as interstitial pneumonia, highlights the need for a tailored approach to treatment. Some studies suggest that patients experiencing both chronic fatigue and other related symptoms may require more comprehensive treatment strategies, urging further research to fully understand the optimal use of vitamin C in CFS management [3]. Overall, while existing evidence points to potential benefits, the need for ongoing research and individualized treatment frameworks is crucial for those suffering from this multifaceted syndrome.

Based on user reviews, many individuals have reported significant improvements in their symptoms when taking vitamin C for managing chronic fatigue syndrome. Users frequently note increased energy levels and reduced feelings of fatigue after consistent use. For instance, one reviewer highlighted feeling a boost in energy and wellbeing after just two weeks of supplementation, allowing them to engage in physical activities like swimming and jogging ((Read Review)). Another user mentioned feeling greatly invigorated and less lethargic after two months, even reducing their dosage while still experiencing benefits ((Read Review)).

Furthermore, users have expressed that vitamin C helps in enhancing their immune response, leading to fewer colds and quicker recovery times. A reviewer noted significant health improvements—including lifted mood and diminished fatigue—after three months of use ((Read Review)). Similarly, some users found the supplement beneficial for managing symptoms related to hidden anemia and other health issues, which also contributed to an overall increase in wellbeing ((Read Review)). While individual experiences can vary based on personal health conditions and lifestyle, the consensus indicates that many have found vitamin C to be a valuable addition in their pursuit of alleviating chronic fatigue symptoms.

Based on user reviews, many individuals have found that combining this vitamin C supplement with other vitamins or supplements significantly enhances its effectiveness in managing Chronic Fatigue Syndrome (CFS). Several reviewers mentioned pairing vitamin C with folic acid, which they reported improved absorption and consequently better results in terms of energy levels and overall wellbeing. One user specifically noted that taking one tablet with a meal alongside folic acid led to a noticeable reduction in fatigue and a revival of energy for physical activities, describing their satisfaction with the results ((Read Review)).

Moreover, some users have highlighted the effectiveness of taking vitamin C with B group vitamins for an amplified impact on fatigue. One user stated that alongside their intake of vitamin C, the B group vitamins significantly aided their fight against chronic fatigue, making waking up in the mornings much easier ((Read Review)). Another user observed that sufficient vitamin C levels helped mitigate symptoms worsened by taking large amounts of niacin, which was linked to their allergies affecting their chronic fatigue symptoms ((Read Review)). These accounts suggest that the strategic combination of vitamin C with other supplements may provide users with enhanced relief from the fatigue associated with CFS.

Based on user reviews, the right dose for Vitamin C when treating Chronic Fatigue Syndrome seems to vary among individuals but commonly falls between one to six tablets daily. Users report taking 1-2 tablets a day with food for optimal benefits, which significantly alleviates feelings of lethargy and fatigue, while also boosting immunity (Read Review). Some users, like one who takes 3-5 tablets daily, experienced improved energy levels and an easier morning wake-up routine (Read Review). Another user shared their positive experience using 6 tablets daily, attributing their recovery in energy and overall health to the time-release formula (Read Review).

Additionally, some reviewers noted that after a period of consistent intake, they reduced their dosage while still enjoying the energy and immune-boosting benefits (Read Review). This suggests that starting with a higher dose and adjusting based on individual response might be a practical approach. Overall, users appear to find substantial relief from fatigue when incorporating Vitamin C in their daily routine, sometimes in conjunction with other vitamins for enhanced absorption and effects (Read Review).

9
Vitamin C therapy shows potential
We investigated the effects of high dose intravenous vitamin C on patients suffering from chronic fatigue syndrome (CFS) linked to Epstein-Barr virus (EBV) infections. Our analysis included data from 178 patients who had elevated levels of EBV antibodies, alongside 40 who also showed signs of ongoing viral activity. Most of our participants were diagnosed with chronic fatigue syndrome, while others had related conditions such as mononucleosis or general fatigue.

What we found is quite promising. High doses of vitamin C appeared to reduce the duration of disease symptoms and helped decrease antibody levels associated with EBV. Notably, we observed that patients with higher levels of vitamin C in their plasma generally had lower levels of certain EBV antibodies, suggesting a potential link that might help manage symptoms of CFS.

Furthermore, there was an interesting connection between vitamin D levels and EBV antibodies as well. Patients who had high levels of vitamin D showed lower levels of EBV early antigen antibodies. This points towards a holistic approach to managing CFS, where both vitamin C and vitamin D may play beneficial roles. Overall, our findings hint at an encouraging effect of high dose vitamin C therapy in helping those grappling with CFS due to EBV.
7
Vitamin C effects on CFS
We investigated the potential benefits of vitamin C infusions in treating Chronic Fatigue Syndrome (CFS) through a clinical study. This study looked at patients diagnosed with chronic pneumonia and CFS, focusing on how these patients responded to different vitamin C infusion treatments—both those without the addition of dehydroepiandrosterone (DHEA) and those that included it.

Our analysis revealed that a significant portion of patients experienced symptoms aligning with CFS, characterized by a prolonged illness that required extensive medical care. Patients tended to respond better to a combination of both the old and new vitamin C infusions rather than relying solely on the traditional treatment.

Notably, the combined treatment was more effective, suggesting that there may be underlying issues related to hormone levels in CFS patients that are influenced by vitamin C therapy. However, we also noted potential side effects with the sole use of the new vitamin C infusion. A careful balance between the different infusion approaches is crucial for achieving the best outcomes in CFS management.

Overall, while we observed some promising responses to vitamin C treatments, more research is necessary to fully understand its effectiveness and to optimize treatment strategies for those suffering from chronic fatigue syndrome.
7
Vitamin C aids immune function
We examined how a combination of megadose vitamin C infusions and other treatments might help manage chronic fatigue syndrome, particularly in the context of interstitial pneumonia. Our findings were based on nearly a decade of treating patients, allowing us to gather valuable insights.

We observed that the long-term use of this treatment system significantly reduced the risk of pneumonia recurrence. It also appeared to help prevent the emergence of certain cancers in older patients suffering from interstitial pneumonia. Surprisingly, we found a link between interstitial pneumonia and an increased risk of depression, likely driven by prolonged glucocorticoid use.

While some patients showed promise under this treatment, those battling both interstitial pneumonia and depression responded less favorably. We suggested that increasing the amount of dehydroepiandrosterone in the treatment could be beneficial. Throughout our experience, we noted that the characteristics of chronic fatigue syndrome align closely with those of interstitial pneumonia, arguing against the notion that they should be viewed as separate conditions.

Overall, our approach not only alleviated inflammation but did not suppress the fibrotic processes in the long run. We made modifications to the treatment to lower the risks of vascular complications. The main strength of our treatment lies in creating a hormonal environment that helps tackle immune deficiencies using vitamin C, which faces lower resistance in the body compared to steroid treatments.

References

  1. Mikirova N, Hunninghake R. Effect of high dose vitamin C on Epstein-Barr viral infection. Med Sci Monit. 2014;20:725. doi:10.12659/MSM.890423
  2. Kodama M, Kodama T. Four problems with the clinical control of interstitial pneumonia, or chronic fatigue syndrome, using the megadose vitamin C infusion system with dehydroepiandrosterone-cortisol annex. In Vivo. 2006;20:285.
  3. Kodama M, Kodama T. The clinical course of interstitial pneumonia alias chronic fatigue syndrome under the control of megadose vitamin C infusion system with dehydroepiandrosterone-cortisol annex. Int J Mol Med. 2005;15:109.
  4. Kodama M, Kodama T, Murakami M. The value of the dehydroepiandrosterone-annexed vitamin C infusion treatment in the clinical control of chronic fatigue syndrome (CFS). II. Characterization of CFS patients with special reference to their response to a new vitamin C infusion treatment. In Vivo. 1996;10:585.
  5. Kodama M, Kodama T, Murakami M. The value of the dehydroepiandrosterone-annexed vitamin C infusion treatment in the clinical control of chronic fatigue syndrome (CFS). I. A Pilot study of the new vitamin C infusion treatment with a volunteer CFS patient. In Vivo. 1996;10:575.
image